Genomics and Health group aims to bridge the gap between fundamental
research and clinical care through the characterization and
development of tools and biomarkers to improve health outcomes of
patients. One key objective is to accelerate progress in genomic
research in pathogenomics and human health by cultivating a common
framework of standards for effective genomic and health-related data
This group is actively searching and/or identifying new therapeutic targets to prevent and cure diseases of both the pathogen and host perspectives.
The Microbial Genomics Group contributes expertise and leadership in national and international collaborative projects. It also develops research in a wide array of microbiological models taking advantage of innovative approaches in functional and evolutionary genomics, bioinformatics, and molecular microbiology. The group works with public and private national and international research agencies to explore key questions in microbiological systems using the refined analytical tools now available including next-generation sequencing and cutting-edge biocomputing technologies.
Our group focuses on the study of the interactions between microorganisms and their environment, together with understanding how those complex networks of interactions have contributed to their adaptation and evolution to favor their survival. The main areas of research and development are related to the study of host-pathogen interactions, structural and evolutionary genomics, and microbial and fungal diversity.
Plants are key organisms in our ecosystems and are the basis of nearly all food chains. For humans, more than 50% of food comes from plant sources. Crop productivity is heavily impacted by the current scenario of climate change, together with the appearance of new pests. This leads to an unbalance between food supply and a growing population, which raises concerns about the present and future food security. In order to tackle these problematics, the plant genomics group aims to:
1) Unveil the molecular mechanisms by which plants sense and respond to environmental cues.
2) Characterize the microbial communities associated with extreme plants and the mechanisms of plant communication with other species
3) Preserve and understand the basis of biodiversity of our flora by sequencing the genomes of native plants from Chile.
The Bioinformatics and Computational Biology group is a highly interdisciplinary team that conducts research on the computer,
biological, and mathematical sciences. The group’s strategy is to
integrate computational approaches to explore data sets generated by
high throughput technologies (omics technologies) in order to develop
new concepts, tools, and knowledge to study biological processes and
The group is focused on the study the sequence-structure-function relationship, biological networks, on the understanding of self-regulatory dynamics, the evolution of individuated multicellular organisms, how do biomolecules have expanded and diversified, and how genome novelty can explain phenotypic diversity under different environmental conditions.