31 diciembre 2017

Effect of yeast (Xanthophyllomyces dendrorhous) and plant (Saint John's wort, lemon balm, and rosemary) extract based functional diets on antioxidant and immune status of Atlantic salmon (Salmo salar) subjected to crowding stress

DOI : 10.1016/j.fsi.2017.12.061

DESCARGAR
Sebastián Reyes

Salmon farming may face stress due to the intensive culture conditions with

negative impacts on overall performance. In this aspect, functional feed

improves not only the basic nutritional requirements but also the health status

and fish growth. However, to date no studies have been carried out to evaluate

the effect of functional diets in salmon subjected to crowding stress. Thus, the

aim of this study was to evaluate the effect of yeast extract (Xanthophyllomyces

dendrorhous; diet A) and the combination of plant extracts (common Saint John's

wort, lemon balm, and rosemary; diet B) on the antioxidant and immune status of

Atlantic salmon grown under normal cultured conditions and then subjected to

crowding stress. Fish were fed with functional diets during 30 days (12 kg/m3)

and then subjected to crowding stress (20 kg/m3) for 10 days. The lipid

peroxidation in gut showed that both diets induced a marked decrease on

oxidative damage when fish were subjected to crowding stress. The protein

carbonylation in muscle displayed at day 30 a marked decrease in both functional

diets that was more marked on the stress condition. The expression of immune

markers (IFNγ, CD4, IL-10, TGF-β, IgMmb, IgMsec, T-Bet, and GATA-3) indicated

the upregulation of those associated to humoral-like response (CD4, IL-10,

GATA-3) when fish were subjected to crowding stress. These results were

confirmed with the expression of secreted IgM. Altogether, these functional

diets improved the antioxidant status and increased the expression of genes

related to Th2-like response suggesting a protective role on fish subjected to

crowding stress.

Investigadores Participantes del Centro

Immunogenomics Laboratory

Doctor en Microbiología, Universidad de Santiago, Chile.


LEER MÁS
Edificio2

Contacto

Edificio Corporativo, 1er subterráneo - Campus Huechuraba - Camino La Pirámide 5750, Huechuraba
+56 2 2328 1323|cgbum@umayor.cl