Our interest lies in exploring the interactions between biocontrol fungi and plant pathogens using a systems biology approach. Now, we are focusing on understanding the molecular basis of the mycoparasitism process carried out by the biocontrol fungus T. atroviride. The aim is to delve into the transcriptional mechanisms that regulate the mycoparasitism process to generate new, more sustainable, and environmentally friendly strategies for biological control. This is achieved through understanding and enhancing the mechanisms already present in this organism. To this end, we are conducting various gene expression assays at different stages of the mycoparasitism process with the phytopathogenic fungus B. cinerea (RNAseq- sRNAseq). The information obtained is analyzed through the generation of transcriptional networks, with the purpose of identifying key regulators that control the mycoparasitism process. In this context, we are also evaluating how nutrient availability impacts this process.

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Biography

Biochemistry, Ph.D. in Biological Sciences with a specialization in Molecular Genetics and Microbiology (PUC). She conducted her doctoral thesis on the transcriptional regulation of the circadian clock in Neurospora crassa with Dr. Luis Larrondo at the Pontificia Universidad Católica de Chile. Subsequently, she carried out postdoctoral research at the Center for Plant Biotechnology of the Andrés Bello University, with Dr. Paulo Canessa, studying the role of sRNAs in the interaction between the biocontrol fungus T. atroviride and B. cinerea. Currently, she continues her research focused on studying the interactions between biocontrol organisms and phytopathogenic fungi. Dr. Olivares currently serves as an assistant professor at the Center for Genomics and Bioinformatics at the Universidad Mayor. She is a Young Investigator at the iBIO Millennium Institute and has been the principal investigator of various projects (FONDECYT 11240968, FONDECYT 3190628, REDI17028).

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Selected publications

1. 2021. Olivares-Yañez C., Sánchez E., Pérez-Lara G., Seguel A., Camejo P., Larrondo L., Vidal E., Canessa P. A comprehensive transcription factor and DNA-binding motif resource for the construction of gene regulatory networks in Botrytis cinerea and Trichoderma atroviride. Comput. Struct. Biotechnol. J
2. 2022. Henríquez-Urrutia M., Spanner R., Olivares-Yañez C., Seguel-Avello A., Pérez-Lara R., Guillén-Alonso H., Winkler R., Herrera-Estrella A., Canessa P., Larrondo L. Circadian oscillations in Trichoderma atroviride and the role of core clock components in secondary metabolism, development, and mycoparasitism against the phytopathogen Botrytis cinerea. eLife
3. 2023. Perez-Lara G.*, Olivares-Yañez C.*, Van Bakel H., Larrondo L., Canessa P. Genome-wide characterization of light-regulated gene expression in Botrytis cinerea reveals underlying complex photobiology. Int J Mol Sci. 24
4. 2020. Vasquez-Montaño, E., Hoppe, G., Vega, A., Olivares-Yañez, C., Canessa, P. Defects in the Ferroxidase That Participates in the Reductive Iron Assimilation System Results in Hypervirulence in Botrytis Cinerea. mBio.

Full list of publications

https://scholar.google.es/cita...